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Working solution concentration: 0.22 mg/mL Method for preparing stock solution: mg drug dissolved in L DMSO

Conservative dosing and careful monitoring are essential.

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When administered intracerebroventricularly in animal models, cortistatin selectively enhances deep slow-wave sleep (SWS) without affecting REM sleep or total sleep time

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Starting at 3 months of age, mice received small injections of Deltaran for five days each month until their natural deaths