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Mice were all housed and received the same treatment protocol and handling procedures, differing on just the drug (GHK-Cu), and were assessed with the same behavioral and histological tests and indicators

doi: 10.1097/01.brs.0000142225.07927.29 98 MillecampsITajerianMSageEHStoneLS

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These signals collectively trigger assembly of the NLRP3-ASC-caspase-1 complex, resulting in mature IL-1/IL-18 secretion and gasdermin-D-mediated pyroptosis (101)

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The Lancet 384:13491357 El Mahdy RN, Nader MA, Helal MG, Abu-Risha SE, Abdelmageed ME (2023) Eicosapentaenoic acid mitigates ulcerative colitis-induced by acetic acid through modulation of NF-B and TGF-/EGFR signaling pathways