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This manuscript abides by the ARRIVE guidelines for reporting animal experiments

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Pathological causes of elevated B12 warrant careful consideration: Haematological disorders : Myeloproliferative neoplasms (polycythaemia vera, chronic myeloid leukaemia), acute leukaemia, and lymphoproliferative disorders can increase B12-binding proteins (transcobalamin and haptocorrin), elevating total serum B12 [3] Liver disease : Hepatocellular damage releases stored B12 into circulation

this requires a different BW volume for 10 units=100mcg, so lets adjust for a practical example): If 10mg vial reconstituted with 10ml BW (1000mcg/ml): 5mg = 500 units (5ml) 10mg = 1000 units (10ml) clearly indicating the need for careful planning regarding total volume