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GLP1R Agonism Downregulates Kinase-Mediated Intercellular Signaling in Advanced Prostate Cancer Models To assess downstream GLP1R signaling in prostate cells, we utilized a phospho-proteome profiler to assess kinase signaling after treatment with semaglutide in the CRPC cell lines CWR-R1 and LAPC4-CR and NEPC cell line H660 (Figure 3A, D, G)

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Escobar-Morreale HF, Obregn MJ, Escobar del Rey F