Its also worth repeating here that most GLP-1 side effects occur within the first week or two of beginning the weight loss medication and are usually mild to moderate, decreasing within the first two months
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Tirzepatide has the most extensive published literature, with FDA approval, multiple completed Phase 3 trial programs (SURMOUNT, SURPASS), and extensive real-world evidence
They may prioritize an SGLT2 inhibitor when heart failure or kidney protection is a main concern
For upcoming obesity drugs, key areas of competition are expected to include reducing the number of annual injections, shifting to oral medications, and lowering side effects, muscle loss and rebound weight gain
The rise of single-use pens brings sustainability into focus