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PMID: 35350465 Sikirica V, et al

Enzyme-responsive drug delivery system has been demonstrated, which consist of triblock N-(2-hydroxypropyl methyl) acrylamide (HPMA) conjugated with tetrapeptide linker, which allows the high molecular weight (92 kDa) to degrade into low molecular weight (44 kDa) and deliver the paclitaxel drug at tumor site [54]

Compound 2 forms predominantly hydrophobic interactions with the adjacent residues in TM6

By stimulating the release of growth hormone, it promotes muscle growth, enhances fat metabolism, and improves recovery, all essential for endurance athletes

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