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These mouse studies appear relevant to human disease, as a large number of studies have shown that polymorphisms in PON1 are associated with increased risk for atherosclerosis (265)

Deciphering the catalytic mechanism of superoxide dismutase activity of carbon dot nanozyme

that is, to examine whether absolute rather than relative differences in hazard could be found ( Sensitivity and subgroup analyses Several sensitivity and subgroup analyses were performed

Directly acts as an alpha-2 adrenergic antagonist, elevating blood flow, increasing the release of fat through lipolysis, and stimulating the nervous system for a higher metabolism

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