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Metformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cells
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showed that focusing NMDA-receptor inhibition specifically on neurons that express the GLP-1 receptor was necessary for this effect, whereas linking MK-801 to other gut peptides that are thought to inhibit feeding was no more effective than MK-801 or the GLP-1 analogue alone at reducing body weight
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