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J Biol Chem 267 , 2143221437 (1992)
Deng X, Song Y, Manson JE, Signorello LB, Zhang SM, Shrubsole MJ, et al
Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6
When you're deficient, the symptoms are usually gradual: fatigue, brain fog, low mood, tingling in hands or feet, unexplained weakness
The binding of C-Met to HGF initiates the receptors innate kinase activity, followed by the formation of a multisubstrate docking site for the intracellular junction protein, which recruits signaling molecules due to homologous dimerization and autophosphorylation at Tyr1234 and Tyr1235 and subsequent phosphorylation at Tyr1349 and Tyr1356 at the c-terminal tail (Trusolino et al., 2010)
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