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During seizures, the brains surge in electrical activity increases energy demand, prompting the body to mobilize energy stores, including amino acids like leucine

Chromatin immunoprecipitation Chromatin immunoprecipitation (ChIP) was performed as described previously (Leon et al., 2021)

NFT-dependent activation of the Nrf2 pathway elevates cellular resilience Nrf2/Keap1 ranks among the most relevant cellular signaling elements that combine sensing of oxidative stress with transcriptional activation of downstream targets involved in antioxidant defense

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Angiotensin II stimulates superoxide production in the thick ascending limb by activating NOX4