I hope my friends in the compounding community call out this type of behavior and if I were one of the manufacturers of current approved GLP-1s (Novo Nordisk, Eli Lilly and Company, etc), I would explore legal action against any company who is blatantly abusing #drugshortage loopholes to engage in manufacturing and not #compounding
But for me, this combination addressed the one concern I had about aggressive weight loss compounds
The support of human genetic evidence for approved drug indications
This is the pharmacological basis for CagriSema : in REDEFINE 1, the combination produced 20.4% mean weight loss versus 11.8% for cagrilintide alone and 14.9% for semaglutide alone
Eli Lilly, which makes the GLP-1/GIP drug Mounjaro (tirzepatide), is currently developing retatrutide , the first drug to target receptors for three hormones: GLP-1, GIP, and glucagon
234,235 Glucagon is a hormone secreted by pancreatic -cells that stimulates the liver to release glucose