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"Incretin-based glucose-lowering medications and the risk of acute pancreatitis and malignancies: a meta-analysis based on cardiovascular outcomes trials"
10.1016/j.chest.2019.10.009 [DOI] [PMC free article] [PubMed] [Google Scholar] 80.Torras MA, Faura CA, Schonlau F, Rohdewald P
The Companys lead candidate, pemvidutide, is a unique dual-action therapy targeting both glucagon and GLP-1 receptors in a balanced 1:1 ratio in development for the treatment of metabolic dysfunction-associated steatohepatitis (MASH), alcohol use disorder (AUD) and alcohol-associated liver disease (ALD)
This maybe useful if you have a carer or a family member willing to administer your injection
These studies demonstrate that localized GLP-1R activation enhances cholesterol efflux, reduces plaque lipid burden, and suppresses inflammatory gene expression even at doses too low to alter systemic metabolic parameters