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Amino acids 130 and 3160 constitute two copies of modified human GLP-1, the alanine at position 2 having been exchanged for a glycine for better DPP-4 resistance

Stable blood sugar is important because large fluctuations can lead to hunger and cravings

The medication's appetite-suppressing effects vary considerably between individuals due to differences in metabolism, hormonal regulation, lifestyle factors, and the stage of dose escalation

Initially indicated for the management of type 2 diabetes, significant weight-loss was seen

We have several independent approaches focused on promoting and preserving muscle during weight loss, so as to increase the amount of fat loss since adiposity is the principal driver of comorbidities and metabolic diseases associated with obesity

Abrupt cessation creates a hormonal whiplash that makes weight regain almost inevitable