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Semaglutide is a GLP-1 receptor agonist that, for many patients, provides sufficient appetite control and weight loss support without needing the dual-agonist approach that tirzepatide offers

Most reactions involve mild injection-site irritation

The degree and speed of regain varies, but the pattern is consistent across clinical trials and real-world data

The bottom line on GLP-1 timelines The most important thing to know about the GLP-1 results timeline is that progress takes time

At the suggestion of her endocrinologist, she started semaglutide in April 2022 and switched to tirzepatide after an insurance change, losing 41 pounds so far, and nearing her goal