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In contrast, IGFBP 5 induces cellular adhesion and inhibits migration of MCF7 cells via the activation of AKT in an IGF-independent manner, consistent with previous studies suggesting an apoptotic role for IGFBP 5 in BrCa [68]

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Matsumura N, Kinoshita C, Bhadhprasit W, Nakaki T, Aoyama K (2023) A purine derivative, paraxanthine, promotes cysteine uptake for glutathione synthesis

[DOI] [PMC free article] [PubMed] [Google Scholar] 213.Shetty S, Kusminski CM, Scherer PE

It is highly addictive and withdrawal symptoms may be severe (but rarely fatal in adults)