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Very few address the shared upstream driver: a chronically overactivated stress-hormone system that simultaneously blocks restorative sleep and rewires metabolism toward fat storage and glucose dysregulation

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Cellular Stress Resistance In preclinical models, MOTS-c has also been shown to help cells tolerate metabolic and oxidative stress, which is part of the basis for interest in its potential role in aging and age-related disease

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The completion of a Phase I trial is a significant milestone, as its primary objective is to assess safety and tolerability in human subjects

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