Vicentini GE, Fracaro L, de Souza SRG, Martins HA, Guarnier FA, Zanoni JN
Furthermore, a different approach using intragastrically administered rotenone (5 mg/Kg) in mice showed that the accumulation and aggregation of -synuclein in neurons of the dorsal motor nucleus of the vagus (DMV) and the intermediolateral nucleus (IML) in the spinal cord was accompanied by the selective loss of dopaminergic neurons and astrogliosis, suggesting that the gastric administration of rotenone through the connection of the enteric nervous system (ENS) with anatomical structures of the CNS also induces PD-like features [11,19]
180 Vascular remodeling refers to a series of structural and functional abnormalities in the vascular wall, including the proliferation, migration, and apoptosis of cells within the vessel wall, and changes in the matrix components
Thus, gut fungi may serve as biomarkers for HCC progression and potential targets for preventive or therapeutic interventions
Spinal Cord Injury BPC 157 has shown great promise in enhancing recovery processes following spinal cord injuries
It could also be due to the adipocyte dysfunction linked to low vitamin B12 levels through cellular inflammation