Branched fatty acid esters of hydroxy fatty acids are preferred substrates of the MODY8 protein carboxyl ester lipase
doi:10.1161/01.CIR.0000165142.37711.E7 [17] Nelen WL, Blom HJ, Steegers EA, den Heijer M, Thomas CM, Eskes TK
In consequence, acylcarnitines constitute an appreciable component of the tissue carnitine pool, and tissue and plasma concentrations of carnitine and acylcarnitines are together maintained within relatively narrow limits by a variety of mechanisms, which influence in turn innumerable aspects of carbohydrate and lipid metabolism, including the regulation of insulin secretion by pancreatic -cells and the determination of tissue insulin sensitivity
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Etap dual podwjne agonisty GLP-1 i GIP (jak tirzepatyd), aktywujce dwa receptory naraz