When a peripheral nerve fiber is damaged, the portion of the axon beyond the injury point degenerates through a process called Wallerian degeneration
These aggressors cause whats known as cellular destabilization, which leads to signs of aging, like sagging skin, fine lines, rough texture, and hyperpigmentation
GLP-1 use is safe and effective with many pre-existing conditions with the exception of the following: Currently pregnant Currently breastfeeding Currently being treated for cancer Active eating disorder Active gallbladder disease Active substance abuse or dependency Type 1 diabetes Bariatric surgery (within the past 18 months) Pancreatitis within the past 6 months, or a history of pancreatitis caused by taking a GLP-1 Personal or family history of medullary thyroid cancer or MEN syndrome Personal history of Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
Filippatos G, Anker SD, August P, et al
Last reviewed: June 1, 2026 Last updated: June 1, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
Reduced glutathione (the active form) oxidizes rapidly at room temperature a study in the Journal of Pharmaceutical Sciences found 40% potency loss within 14 days at refrigerator temperature and up to 80% loss within 7 days at room temperature
