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Quick Answer: The primary difference lies in bioavailability

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Research consistently shows that consuming 1.2-1.6 grams of protein per kilogram of body weight daily significantly reduces lean mass loss during caloric restriction

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In the model presented to NICE, the company said those in the trial were provided with advice including leaflets on healthy diet, smoking cessation and physical activity which is similar to what already happens in cardiovascular risk management, so they had not included a separate cost for this