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Una proporcin relevante del corpus comparte grupos y marcos experimentales

AOD-9604 has a comparatively limited safety database, which is its own problem

Generally well-tolerated in animal studies with no major organ toxicity observed

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The PPP in erythrocytes is the only pathway for these cells to produce NADPH, therefore, any defect in the production of NADPH, such as due to deficiencies in glucose-6-phosphate dehydrogenase, will have profound effects on erythrocyte survival