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Cancer Res 69, 44934501 (2009)

The authors reported that high intracellular levels of the lactone caused apoptotic cell death by upregulation of COX-2 mRNA and protein, as well as increased formation of peroxisome proliferator activated receptor (PPAR)-activating PGD2

Pharmacological options : NICE recommends considering antidepressants such as amitriptyline or duloxetine for pain management

As prospects, further studies can be conducted to evaluate the effect of acute treatment with NAC and ALC in higher concentrations on PTZ-induced seizures

However, it is important to note that results from animal experiments may not directly apply to humans

Making digoxin therapeutic drug monitoring more effective