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Common causes of B12 deficiency include poor dietary intake, certain medical conditions (such as pernicious anemia or gastrointestinal disorders), and the bodys decreased ability to absorb B12 with age

A., & Frishman, W

Less serotonin in the brain has been linked to depressive symptoms

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These effects are particularly significant given the complex interplay between hypothyroidism, immune dysregulation, and metabolic disturbances (Fujii et al., 1989

Mass spectrometry (MS): LC-MS and LC-MS/MS provide the highest specificity and sensitivity for glutathione analysis