Among these, GHK upregulated 47 DNA repair genes and modulated pathways relevant to follicle stem cell maintenance (Pickart et al., 2015)
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Third, the APR-017 and LCS3 induced increase in ROS, decrease in GSH, and inhibition of cell growth in VRK2-KO cells could be reversed by supplying a GSH compensator
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These may include minor side effects such as a little redness, swelling, or slight bruising at the injection site, which typically resolve quickly
GSH is a tripeptide antioxidant, in which its synthesis is catalyzed by GCS and GSH synthetase from glutamate, cysteine and glycine