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There are some proposed theoretical concerns about tissue repair or angiogenesis (cancer-prone) but not substantiated
In rat pups and young piglets, dietary deprivation of glutamine has been reported to diminish intestinal integrity, through breakdown of epithelial junctions and shortening of microvilli (119, 120)
Remarkably, ER-, but not ER-specific ligands, lead to increased phosphorylation of ERK 1/2, which initiates cell cycle entry (demonstrated by the up-regulation of mitotic markers such as CDK1/cdc2 and PCNA), DNA replication, and duplication of the centrosome -the major microtubule-organizing center in the cell- in dividing cells (Wang et al., 2008)
10.2174/138527210790231919 27 AsgherM.QamarS
Detection was performed using a UV detector at 220 nm
FEBS Lett (2015) 589:155968
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