Thanks William N SW Florida
In a diabetes-driven kidney disease model, Glp1r / mice with streptozotocin-induced diabetes exhibited spontaneous kidney dysfunction and accelerated kidney damage as evidenced by their higher albumin-to-creatinine ratios, increased fibronectin levels, and lower cystatin C levels in the urine (70)
For this particular drug its a race, because its a category changer that has come out of nowhere, adds Johnson
Possible Side Effects and Risks Side effects can vary depending on the peptide, route of administration, dose, formulation, sourcing, and patient health history
Tirzepatide (Zepbound) is a drug that works in two ways
Stimulating these central amygdalar neurons curtails hedonic feeding, whereas targeted deletion of the receptor in this cell population specifically diminishes the anorectic efficacy of GLP1RAs for reward-driven intake