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sphingomyelin is the most abundant nuclear sphingolipid, and in addition to being an integral part of the nuclear matrix, it also plays structural and regulatory roles in chromatin assembly and dynamics (Yuan et al., 2024)

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Peer review Peer review information Nature Metabolism thanks Xun Huang and the other, anonymous, reviewer for their contribution to the peer review of this work

Long-term weight patterns and physical activity in gallstones