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However, the therapeutic utility of doxorubicin is undermined by its dose-dependent cardiotoxicity, possibly arising as a result of futile redox cycling, with NADH dehydrogenase within the mitochondria proposed as the most likely site of anthracycline reduction 9,10

To eliminate that confusion and provide a more precise description, weve adopted the terminology pentadeca short-chain amino acids. Pentadeca means 15, referring to the 15-amino-acid sequence that defines this compound

Abd El Aziz MS, Meier JJ, Nauck MA

2009 Aug;161(2):419-426

doi: 10.1016/j.parkreldis.2009.05.005 95 FanZAmanYAhmedIChetelatGLandeauBRay ChaudhuriKet al

8.4 Clinical differentiation in a post-GLP-1 landscape The success of incretin-based therapies has raised expectations for efficacy in metabolic disease, particularly in obesity, where benchmarks for weight loss and cardiometabolic improvement are now well established (Kushner and Kahan, 2024)