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When MIC B12 Injections Can Help Confirmed B12 deficiency: Injectable B12 is a standard medical therapy and can be important when absorption is impaired (NIH ODS overview: Vitamin B12 fact sheet )

Vitamin B12 injections are most clinically appropriate in cases of confirmed vitamin B12 deficiency, malabsorption syndromes including pernicious anaemia or post-gastric surgery, significant symptoms where rapid restoration of vitamin B12 levels is required, or failure of oral supplementation due to poor absorption

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The mechanism research has produced both basic-science findings on the molecular targets and translational-research observations in disease-model systems

Dietary supplements are products intended to supplement the diet

Over-supplementing can be harmful as well, especially for B6, since high doses over time may be linked to nerve damage, and studies show that getting too much of either type of B vitamin may be detrimental to bone health