For example, a previous study on PD brains showed an increase in lipid peroxidation products, such as 4-hydroxinonenal, and in protein crosslinking and fragmentation [51], suggesting that oxidative stress may affect other brain regions apart from the SN
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In vitro , in comparison with control, healthy animals, the assessment of splenic cells (day 21) demonstrated that the 6-methylprednisolone animals had declined reactivity to nitrogen, while the addition of BPC 157 (1 g/g cream) returned cell reactivity to normal values (Mikus et al., 2001
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doi: 10.1016/j.mehy.2005.03.013 23 ParkMHKwonYJJeongHYLeeHYHwangboYYoonHJet al
doi: 10.1007/s11571-018-9503-3 40 NivenJE
