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It has been shown that GLP-1/the GLP-1R agonist exendin-4 increases GABA A R-mediated tonic currents through GLP-1R activation in rat hippocampal CA3 pyramidal neurons [14], but no data concerning the regulation of GABARs of retinal neurons by GLP-1/GLP-1R agonists are now available

GLP-1 receptor agonists have been associated with improved kidney function and a reduced risk of kidney failure in individuals with type 2 diabetes and chronic kidney disease

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Overviews of some of the major studies are presented here

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