doi:10.1111/dom.12924 MacLean PS, Wing RR, Davidson T, Epstein L, Goodpaster B, Hall KD, Levin BE, Perri MG, Rolls BJ, Rosenbaum M, Rothman AJ, Ryan D
Therefore, it might be useful to expand the evidence on high-dose liraglutide, also considering that there are no direct studies that compare high-dose liraglutide and metformin
It also contributes to cellular hydration, which can further stimulate anabolic signaling
Kyle UG, Bosaeus I, Lorenzo D, Deurenberg AD, Elia P, Gmez M, et al
However, a 2025 review noted only 3 RCTs, calling for larger trials (Nguyen et al., 2025)
PlexusDx supports this decision-making by offering both compounded medications and genetic insight tools