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However, full effects on metabolism and other areas may take 4-6 weeks as it takes time for levels to build up in the body

These trials included both single-dose pharmacokinetic studies and long-term efficacy trials extending up to 24 weeks of continuous administration

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[DOI] [PMC free article] [PubMed] [Google Scholar] 164.Mndez-Andino JL, Wos JA

The first criterion, at 419.66(c)(1), provides that CMS determines that a device to be included in the category is not appropriately described by any of the existing categories or by any category previously in effect, and was not being paid for as an outpatient service as of December 31, 1996