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All three peptides show promising results in preclinical and early clinical studies, but further research is needed to confirm their long-term safety and efficacy

Sue DeCotiis, who specializes in regenerative medicine and prescribes GLP-1 medications in her practice, said retatrutide works by adding a third hormonal pathway glucagon on top of the dual GLP-1 and GIP mechanism already found in tirzepatide, sold as Mounjaro and Zepbound

They neutralize stomach acid, causing a reduction in gas production