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"The adipose tissue (AT) expandability hypothesis explains that the individual capacity to appropriately store energy surplus as fat within the AT prevents the toxic deposition of lipids in other organs, such as the pancreas. Looping back to the role of the brain in obesity, I would move one level higher in the cascade of downstream effects - to the central regulation of hedonic appetite and the wiring of the reward system, overexpressed obesogenic genes within the CNS, and the role of ultra-processed food

About the Author SUZANNE SOMERS is the author of 25 books, including the #1 New York Times bestsellers Sexy Forever, Knockout, Ageless, and the New York Times bestsellers I'm Too Young For This

Kaufman believes that the fact that GLP-1 receptors are found all over the body explains why these drugs can have so many effects