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This role is mediated by multiple cytokines, growth factors and death receptor-ligand systems that execute their effect on erythropoiesis partially through apoptosis modulation

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In recent years, glutathione has been aggressively marketed as a wonder drug that could brighten complexion and balance skin tone, particularly when injected or applied topically

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In this context, the antitumor activity reported for incretin-based polyagonists should not be interpreted as evidence for GCGR agonism alone, but rather as an indication that coordinated multi-receptor targeting may induce favorable systemic metabolic remodeling (62,63)

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