Abbreviations MAFLD: Metabolic dysfunction-associated fatty liver disease MASH: Metabolic dysfunction-associated steatohepatitis LC-MS: Liquid chromatography-mass spectrometry UPLC-Orbitrap-MS/MS: Ultra-performance liquid chromatography coupled with Orbitrap tandem mass spectrometry ALT: Alanine transaminase AST: Aspartate transaminase TG: Triglycerides TC: Total cholesterol HDL-C: high-density lipoprotein cholesterol LDL-C: Low-density lipoprotein cholesterol HFD: High-fat diet NCD: Normal diet group GLP-1: Glucagon-like peptide-1 GIP: Glucose-dependent insulinotropic polypeptide HE: Haematoxylin and eosin ORO: Oil Red O HRI: hepatorenal index DIA: Data-independent acquisition DDA: Data-dependent acquisition PRM: Parallel reaction monitoring PPI: Protein-protein interaction M6P: D-mannose-6-phosphate References Riazi K, Azhari H, Charette JH, et al

Heres a breakdown of common gastrointestinal side effects and their frequency, based on findings from the SURMOUNT-1 trial: To ease nausea and other digestive issues, consider these tips: Understanding potential side effects and how to address them is key to sticking with your treatment plan
Ridley, F
Eur J Nutr 54:251263 Schmitt B, Vicenzi M, Garrel C, Denis FM (2015) Effects of N-acetylcysteine, oral glutathione (GSH) and a novel sublingual form of GSH on oxidative stress markers: a comparative crossover study
Li K, Lin C, Li M, Xu K, He Y, Mao Y, Lu L, Geng W, Li X, Luo Z, Cai K
The table below shows how the two medications compare