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Compared to monotherapies or conventional combination regimens, programmable nanoplatforms achieve personalization through three integrated mechanisms that include spatial targeting, physiological responsiveness, and AI-assisted optimization

CSCs are a subset of aberrant cells that possess the unique capacity for self-renewal and differentiation, playing a crucial role in tumor initiation, progression and metastasis throughout the tumorigenesis process (59)

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However, early findings suggest that GLP-1 receptor agonists may actually have some protective effects in the gut