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Therefore, in the present study, cultured microglia were exposed to OGD/R to mimic ischemia/reperfusion injury in vitro and were used to determine whether Sirt1 could regulate microglial activation and inflammation following OGD/R injury in vitro and whether these effects were mediated via Shh/GLI family zinc finger-1 (Gli-1) signaling

Peptides may penetrate tissues more effectively than larger proteins due to their smaller size

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Gastric retention measured at 30 minutes post-meal showed dose-dependent improvement: 10 g/kg reduced retention by 22%, 100 g/kg by 41%, and 10 mg/kg by 58% compared to untreated controls

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