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Abstract Paclitaxel, a cornerstone taxane for solid-tumor chemotherapy, frequently precipitates long-lasting cognitive deficits, which are collectively termed chemotherapy-related cognitive impairment and often referred to as chemobrain or chemofog

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Injecting MTX to carnitine-depleted rats caused 98% and 67% reduction in serum total carnitine and 98% and 65% reduction in serum free carnitine compared to control and MD groups, respectively