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TSH is the most sensitive marker, and high TSH and low free T4 confirm primary hypothyroidism

doi:10.21037/tau.2018.08.14

Given an inferior performance of individual biomarkers in diagnosing early PD, combination of multiple biomarkers may greatly improve the diagnostic efficacy

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Studies conducted in laboratory settings show that exposure to A leads to a shift from using oxidative phosphorylation to aerobic glycolysis, similar to the Warburg effect

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