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Patients who continue refills indefinitely without documented clinical benefit are spending money on habit rather than effective therapy
The foundation of this detoxification function lies primarily in the presence of an active thiol group on the cysteine side chains in GSH
Very high HbA1c at diagnosis (above 10 percent) with hyperglycemic symptoms
A more detailed assessment score than NDS is the Neuropathy Impairment Score (NIS), which evaluates: muscle strengthtested in eight muscle groups through flexion and extension, scored from 0 to 4, where 0 is normal and 4 indicates no activity and sensitivity and reflexesincludes vibration, touch, sharp stimulus and position sense
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