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The spate of issues is causing concern for brand-name drugmakers, who are working to protect their products reputations

Lesser reports were noted for other GLP-1 agonists, with dulaglutide contributing 65 reports, liraglutide showing 20, and exenatide only six

69,70 Concurrently, the Wnt/-catenin pathway contributes to self-renewal via TCF/LEF-mediated transcription of stemness-related genes, although excessive activation of this pathway can cause aberrant proliferation

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These changes are generally temporary as your digestive tract adjusts to a lower caloric load