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Most patients experience their first side effects within 24 to 72 hours after the initial injection, though timing varies based on individual metabolism and genetic factors

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Succinyl-CoA also is required for hemoglobin synthesis.2,4 B12 digestion and absorption requires the adequate synthesis of hydrochloric acid, proteases (enzymes that break down proteins and peptides), and intrinsic factor (a glycoprotein secreted in the stomach)

Additionally, cannabis-related cognitive impairment might reduce awareness of hypoglycaemic symptoms (low blood sugar), such as tremor, sweating, or confusion, potentially delaying appropriate treatment

Symptoms include severe abdominal pain that may radiate to your back, nausea, and vomiting that does not let up

Catching these early avoids pain and prevents treatment delays