81,82 Aging also promotes the proinflammatory polarization of monocytes by increasing the plasma saturated fatty acid concentration, thereby increasing the production of IL-6 and TNF- but inhibiting the production of IL-10 and transforming growth factor- (TGF-1)
These outcomes translate to improved blood sugar control, reduced cardiovascular risk, and often decreased need for other medications
Potency inconsistencies are a documented issue, and patients who have been self-adjusting based on online dosing guides are at real risk of either under-dosing and seeing no results or over-dosing and dealing with serious side effects
This isn't just a list of facts
Recent studies have also found that the GHR-JAK2-STAT5 signal inhibits lipid uptake and neo-adipogenesis in the liver, partly by inhibiting PPAR and downstream CD36 (Sos et al., 2011
10.1016/j.cden.2010.08.010 167 ZhangB.SunY.ChenL.GuanC.GuoL.QinC