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The mechanism is not fully established, but the preservative may offer a mild stabilizing effect on certain peptide bonds

Any disruption along this pathway can lead to deficiency regardless of dietary intake, which is why some patients need supplementation even when they eat B12-rich foods

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This is a hereditary condition and occurs in Australian Shepherds, Border Collies, Chinese Shar-Peis, Beagles, and Giant Schnauzers

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