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Because tirzepatide activates a broader receptor footprint, it is studied as a model for combinatorial incretin pharmacology rather than single-pathway agonism

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June 2025 On June 6, 2025, the European Medicines Agencys (EMA) safety committee concluded that Novo Nordisks semaglutide-containing drugsincluding diabetes treatment Ozempicmay cause rare but serious cases of non-arteritic anterior ischemic optic neuropathy (NAION), a sudden and painless vision loss in one eye due to optic nerve damage

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