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Charge variants and aggregates may become more significant during downstream processing, formulation, or due to inadequate purification conditions, underscoring the necessity for careful attention to the purification conditions we employ

Japan: No clear pathway for GLP-1 claims Japans FOSHU system, which had around 11,00012,000 approved products by FY2023, does not provide a clear route for GLP-1-related claims

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As a result, stakeholders prescribing, receiving, or dispensing compounded semaglutide injection products need to take immediate action to plan and adapt accordingly