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The Joint Surprise Surprise number four, and this one is remarkable

The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis

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Limited evidence suggests only modest effects in specific populations, with results highly variable and often reversible upon discontinuation

Side effects mirror the injectable, primarily GI issues like nausea, but may intensify temporarily during the switch

Data availability The data used are available upon request from the corresponding author