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Endothelin receptor antagonism prevents hypoxia-induced mortality and morbidity in a mouse model of sickle-cell disease

It facilitates protein and enzyme synthesis, which are essential for cell regeneration

Mutations in the CBS gene can cause disorders like Downs syndrome and peripheral neuropathy

In contrast, in the ELIXA trial (once-daily lixisenatide) [29], neither an increase nor a decrease in MACE and the individual component CV events was observed during the follow-up duration (median 2.1 years)

However, its role in non-steroidogenic cells remains poorly understood

Ben-Meir A, Burstein E, Borrego-Alvarez A, et al